Bioprocessing, commonly known as biopharmaceutical manufacturing, falls under bioprocess engineering used in the cultivation of therapeutic cells. The end products of bioprocessing are high value products and used to work on specific target. Two types of processes are used in biopharmaceutical manufacturing: upstream biopharmaceutical manufacturing and downstream biopharmaceutical manufacturing. The steps involved in upstream biopharmaceutical manufacturing process are development of media, cell culture, harvesting of cells, and fermentation. The biopharmaceutical manufacturing process is carried out under aseptic condition at constant temperature.
The pH levels are adjusted according to microorganism used and are monitored during the entire process. The upstream process provides optimum environment required for the growth of cells. Upstream biopharmaceutical manufacturing is used for large scale cultivation of proteins, vaccines, hormones, antibiotics, enzymes, and other therapeutic products. The products thus obtained from biopharmaceutical manufacturing are used to treat chronic diseases such as immunogenic disorders, diabetes mellitus, and other deficiencies related to growth hormones.
The global Upstream Biopharmaceutical Manufacturing Process Market is driven by increasing prevalence of chronic. Continuous technological innovation has led to high yield of biopharmaceutical production, as technology aims at faster and easier process of production. Additionally, increase in awareness about application of upstream process in cell therapy, cell banking, antibody production, drug discovery, and recombinant proteins accelerate the growth of the upstream biopharmaceutical manufacturing process market. High cost of establishing an upstream processing unit and its maintenance acts as a restraint of the market.
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The global upstream biopharmaceutical manufacturing process market can be segmented based on cell type, process type, product type, end-user, and region. In terms of cell type, the global market can be bifurcated into bacterial cell and mammalian cell. Based on process type, the global upstream biopharmaceutical manufacturing process market can be categorized into continuous biopharmaceutical process systems and single-use biopharmaceutical process system. In terms of product type, the global market can be classified into fermenters and bioreactors. Based on end-user, the global upstream biopharmaceutical manufacturing process market can be divided into contract manufacturing organizations (CMOs), contract research organizations (CROs), biopharmaceutical companies, and academic and research institutes.
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